Cyrus

John C. Reilly

as

John Kilpatrick

Jonah Hill

as

Cyrus Fawcett

Marisa Tomei

as

Molly Fawcett

Catherine Keen...

as

Jamie

Matt Walsh

as

Tim

Kathy Ann Witt...

as

Ashley

Diane Mizota

as

Thermostat Girl

Katie Aselton

as

Pretty Girl

Jamie Donnelly

as

Pastor

Tim Guinee

as

Roger

Steve Zissis

as

Rusty

Bill 'Bunky' M...

as

Cyrus

Charlie Brewer

as

Stranger at Re...

Mitch Carter

as

Additional Voi...

Newell Alexand...

as

Additional Voi...

Steve Alterman

as

Additional Voi...