With Friends Like These...

Bill Murray

as

Maurice Melnick

Adam Arkin

as

Steve Hersh

David Strathai...

as

Armand Minetti

Jon Tenney

as

Dorian Mastand...

Robert Costanzo

as

Johnny DiMarti...

Amy Madigan

as

Hannah DiMarti...

Laura San Giac...

as

Joanne Hersh

Elle Macpherson

as

Samantha Masta...

Lauren Tom

as

Yolanda Chin

Beverly D'Ange...

as

Theresa Carpen...

Martin Scorsese

as

Self

Allison Bertol...

as

Dana Dimartino

Michael McKean

as

Dr. Maxwell He...

Armando Pucci

as

Dr. Puccini

Neal Lerner

as

Poker Buddy - ...

John Mariano

as

Poker Buddy - ...

Jon Polito

as

Rudy Ptak

Greg Grunberg

as

Rudy's Assista...

Garry Marshall

as

Frank Minetti

John Capodice

as

Actor Friend

Tracy Reiner

as

Scorsese Assis...