In a distant galaxy where intelligent apes rule and humans are reduced to little more than breeding stock, a daring escape from a prison ship sparks a desperate fight for survival. This initial clash on an ape-dominated planet soon escalates, leading to the brutal subjugation of Earth and a massive human revolt. But when the conflict expands into a cosmic war involving alien predators, fanatical cults, and corporate greed, both apes and humans must face the terrifying possibility that their struggle for dominion is about to cost them their entire universe.